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ATXN3 Antibody

CAT: 0667-KC-45712-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-45712-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein
Gene Name
ATXN3
Gene ID
4287
UniProt
P54252
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human ATXN3
Target
PP-313
Partner Proteins
Ataxin-3; Machado-Joseph disease protein 1; Spinocerebellar ataxia type 3 protein
Clone
KBL021_4A11
Conjugation
Unconjugated
Applications
Top_IHC&Top_WB
Validation
Top_IHC&Top_WB
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%, Pig - 98%, Cynomolgus monkey - 99%
Purity
≥85%
Cores
GSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIRVQQMHRPKLIGEELAQLKEQRVHKTDLERVLEANDGSGMLDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSGTNLTSEELRKRREAYFE
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
92%
Recombinant Antibody
Not recombinant
IHC Dilution
1:100~1:200
WB Dilution
1:1000
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
ATX3; MJD; MJD1; SCA3
Target Alternative Name
ATXN3
Panel Description
Neurodegenerative Diseases Marker, Neuroscience Biomarkers, Ubiquitin-Proteasome System
Host or Source
Mouse
Protein Name
Ataxin 3
WB Description
Succeed
IHC description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · P54252

Ataxin-3

ATX3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P54252
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ATXN3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.19.12
Processing
—
Secondary accessions
A7LFZ5, D6RDL9, E9PB63, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingTriplet repeat expansion

Molecular function

HydrolaseProteaseThiol protease

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

LysosomeMembraneNucleus

Disease

NeurodegenerationSpinocerebellar ataxia

Domain

Repeat

Biological process

TranscriptionTranscription regulationUbl conjugation pathway

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