PD-L1 Antibody

CAT: 0667-KC-27766-01Size: 50 μLDry Ice: NoHazardous: No

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CAT#:0667-KC-27766-01Size:50 μL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Product Name Alternative

Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD antigen CD274

Gene Name

CD274

Gene ID

29126

UniProt

Q9NZQ7

Antigen Species

Human

Reactivity

Human

Cross Reactivity

Not tested

Immunogen

Recombinant human CD274

Target Antigen

CD274

Target

P00657PCGND

Partner Proteins

Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; hPD-L1; B7 homolog 1; B7-H1; CD antigen CD274

Clone

K06145_8A10

Conjugation

Unconjugated

Applications

Validation

Dilution

1:100

Homology

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 31%, Pig - 80%, Cynomolgus monkey - 96%

Purity

≥85%

Cores

VTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELP

Storage Temperature

Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower

Identity Mouse

73%

Recombinant Antibody

Not recombinant

Formulation

Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide

Antibody Type

Monoclonal

Gene Name Synonym

B7H1; PDCD1L1; PDCD1LG1; PDL1

Target Alternative Name

PD-L1

Panel Description

CD Antigen

Host or Source

Mouse

Protein Name

CD274 molecule

IP description

Fail (HCT116, Raji)

FC description

Succeed

Shipping Temperature

Shipped at ambient temperature or with ice packs.

Isotype

IgG2b

UniProtKB · Q9NZQ7

Programmed cell death 1 ligand 1

PD1L1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9NZQ7
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CD274
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1
EC number: —
Processing: Precursor
Secondary accessions: B2RBA2, B4DU27, Q14CJ2, Q2V8D5, Q66RK1, Q6WEX4, Q9NUZ5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeMembraneNucleusSecreted

Disease

Diabetes mellitus

PTM

Disulfide bondGlycoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Receptor

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