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Furin Antibody

CAT: 0667-KC-7386-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-7386-01Size:50 μL
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Product Name Alternative
Furin, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE
Gene Name
FURIN
Gene ID
5045
UniProt
P09958
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human FURIN
Target
PP-146
Partner Proteins
Furin; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACE
Clone
K1E065_1F10
Conjugation
Unconjugated
Applications
ELISA
Validation
ELISA
Detection Method
Succeed
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%, Pig - 96%, Cynomolgus monkey - 99%
Purity
≥85%
Cores
QEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLP
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
96%
Recombinant Antibody
Not recombinant
Sandwich ELISA Dilution
1:200
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
FUR; PACE; PCSK3
Target Alternative Name
Furin
Panel Description
Ferroptosis
Host or Source
Mouse
Protein Name
Furin, paired basic amino acid cleaving enzyme
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · P09958

Furin

FURIN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09958
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FURIN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.75
Processing
Precursor
Secondary accessions
Q14336, Q6LBS3, Q9UCZ5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Autocatalytic cleavageCleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinZymogen

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeGolgi apparatusMembraneSecreted

Molecular function

Heparin-bindingHydrolaseProteaseSerine protease

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix