SIRT1 Antibody

CAT: 0667-KC-7276-01Size: 50 μLDry Ice: NoHazardous: No

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CAT#:0667-KC-7276-01Size:50 μL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Product Name Alternative

NAD-dependent protein deacetylase sirtuin-1, hSIRT1, NAD-dependent protein deacylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2) [Cleaved into: SirtT1 75 kDa fragment, 75SirT1]

Gene Name

SIRT1

Gene ID

23411

UniProt

Q96EB6

Antigen Species

Human

Reactivity

Human

Cross Reactivity

Not tested

Immunogen

Recombinant human SIRT1

Target

PP-944

Partner Proteins

NAD-dependent protein deacetylase sirtuin-1; hSIRT1; NAD-dependent protein deacylase sirtuin-1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2) [Cleaved into: SirtT1 75 kDa fragment; 75SirT1]

Clone

K06319_4A8

Conjugation

Unconjugated

Applications

ELISA

Validation

ELISA

Detection Method

Succeed

Homology

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%, Pig - 84%, Cynomolgus monkey - 96%

Purity

≥85%

Cores

CCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSD

Storage Temperature

Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower

Identity Mouse

82%

Recombinant Antibody

Not recombinant

Sandwich ELISA Dilution

1:200

Formulation

Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide

Antibody Type

Monoclonal

Gene Name Synonym

SIR2L1

Target Alternative Name

SIRT1

Panel Description

Ferroptosis

Host or Source

Mouse

Protein Name

Sirtuin 1

Shipping Temperature

Shipped at ambient temperature or with ice packs.

Isotype

IgG1

UniProtKB · Q96EB6

NAD-dependent protein deacetylase sirtuin-1

SIR1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q96EB6
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SIRT1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: hSIRT1
EC number: 2.3.1.286
Processing: —
Secondary accessions: Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoproteinS-nitrosylationUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisBiological rhythmsDifferentiationHost-virus interactionMyogenesisTranscriptionTranscription regulation

Cellular component

CytoplasmMitochondrionNucleus

Molecular function

Developmental proteinTransferase

Ligand

Metal-bindingNADZinc

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Alternative Products

Catalog	Name
GTR18158376-01	SIRT1 Antibody