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Caspase-1 Antibody

CAT: 0667-KC-38360-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-38360-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45) [Cleaved into: Caspase-1 subunit p20, Caspase-1 subunit p10]
Gene Name
CASP1
Gene ID
834
UniProt
P29466
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human CASP1
Target
PP-1837
Partner Proteins
Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Clone
K9N054_6D5
Conjugation
Unconjugated
Applications
Top_IHC&WB
Validation
Top_IHC&WB
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 63%, Pig - 73%, Cynomolgus monkey - 89%
Purity
≥85%
Cores
MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
62%
Recombinant Antibody
Not recombinant
IHC Dilution
1:100~1:200
WB Dilution
1:1000
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
IL1BC; IL1BCE
Target Alternative Name
Caspase-1
Host or Source
Mouse
Protein Name
Caspase 1
WB Description
Succeed
IHC description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · P29466

Caspase-1

CASP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P29466
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-1
EC number
3.4.22.36
Processing
Precursor
Secondary accessions
B5MDZ1, Q53EY6, Q6DMQ1, Q6GSS3, Q6PI75, Q9UCN3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Cellular component

Cell membraneCytoplasmMembrane

Molecular function

HydrolaseProteaseThiol protease

PTM

Isopeptide bondPhosphoproteinUbl conjugationZymogen

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