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AMPK alpha 1 Antibody

CAT: 0667-KC-20699-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-20699-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1
Gene Name
PRKAA1
Gene ID
5562
UniProt
Q13131
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human PRKAA1
Target
PP-1416
Partner Proteins
5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1
Clone
K29067_14E7
Conjugation
Unconjugated
Applications
Top_IP/ChIP
Validation
Top_IP/ChIP
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%, Pig - 96%, Cynomolgus monkey - 100%
Purity
≥85%
Cores
ITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMC
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
94%
Recombinant Antibody
Not recombinant
IP Dilution
1:100
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
AMPK1
Target Alternative Name
AMPK alpha 1
Panel Description
DNA binding & Chromatin, Ferroptosis
Host or Source
Mouse
Protein Name
Protein kinase AMP-activated catalytic subunit alpha 1
IP description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2a

UniProtKB · Q13131

5'-AMP-activated protein kinase catalytic subunit alpha-1

AAPK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13131
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKAA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AMPK subunit alpha-1
EC number
2.7.11.1
Processing
—
Secondary accessions
A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

AutophagyBiological rhythmsCholesterol biosynthesisCholesterol metabolismFatty acid biosynthesisFatty acid metabolismHost-virus interactionLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol biosynthesisSterol metabolismTranscriptionTranscription regulationWnt signaling pathway

Molecular function

Chromatin regulatorKinaseSerine/threonine-protein kinaseTransferase

Cellular component

CytoplasmEndosomeNucleus

PTM

GlycoproteinPhosphoproteinUbl conjugation

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