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Recombinant PSEN2 Antibody

CAT: 0667-RC-3041-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-RC-3041-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Presenilin-2, PS-2, AD3LP, AD5, E5-1, STM-2) [Cleaved into: Presenilin-2 NTF subunit, Presenilin-2 CTF subunit]
Gene Name
PSEN2
Gene ID
5664
UniProt
P49810
Antigen Species
Human
Reactivity
Human, Rat, Mouse
Cross Reactivity
Not tested
Immunogen
A synthetic peptide of human Presenilin 2
Partner Proteins
Presenilin-2; PS-2; AD3LP; AD5; E5-1; STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]
Clone
K01_1K52
Conjugation
Unconjugated
Applications
IHC&WB
Validation
IHC&WB
Purity
≥85%
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Recombinant Antibody
Yes
IHC Dilution
1:500
WB Dilution
1:750
Formulation
50mM Tris-Glycine (pH 7.4),0.15M NaCl,40% Glycerol,0.01% Sodium azide and 0.05% BSA
Antibody Type
Monoclonal
Gene Name Synonym
AD4; PS2; PSNL2; STM2
Target Alternative Name
PSEN2
Panel Description
Neurodegenerative Diseases Marker, Neuroscience Biomarkers, Ferroptosis
Host or Source
Rabbit
Protein Name
Presenilin 2
WB Description
Succeed
IHC description
Succeed
IP description
Fail (HeLa)
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG

UniProtKB · P49810

Presenilin-2

PSN2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49810
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PSEN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PS-2
EC number
3.4.23.-
Processing
—
Secondary accessions
A8K8D4, B1AP21, Q96P32
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisCardiomyopathyDisease variantNeurodegeneration

Cellular component

Endoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Molecular function

HydrolaseProtease

Biological process

Notch signaling pathway

PTM

Phosphoprotein

Domain

TransmembraneTransmembrane helix

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