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Recombinant TOP1 Antibody

CAT: 0667-RC-005-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-RC-005-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
DNA topoisomerase 1, DNA topoisomerase I
Gene Name
TOP1
Gene ID
7150
UniProt
P11387
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human TOP1
Target
PP-4377
Partner Proteins
DNA topoisomerase 1; DNA topoisomerase I
Clone
K94015_11B11
Conjugation
Unconjugated
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%, Pig - 99%, Cynomolgus monkey - 100%
Purity
≥85%
Cores
EHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENI
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
97%
Recombinant Antibody
Yes
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
/
Target Alternative Name
TOP1
Panel Description
Autoimmune Disease
Host or Source
Human
Protein Name
DNA topoisomerase I
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · P11387

DNA topoisomerase 1

TOP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11387
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TOP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
5.6.2.1
Processing
—
Secondary accessions
A8KA78, E1P5W3, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Biological process

Biological rhythmsHost-virus interaction

Coding sequence diversity

Chromosomal rearrangement

Molecular function

DNA-bindingIsomeraseTopoisomerase

Cellular component

Nucleus

Disease

Proto-oncogene

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