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Recombinant TPP1 Antibody

CAT: 0667-RN-041-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-RN-041-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Tripeptidyl-peptidase 1, TPP-1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, LPIC, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I
Gene Name
TPP1
Gene ID
1200
UniProt
O14773
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human TPP1
Target
P04459PAD
Partner Proteins
Tripeptidyl-peptidase 1; TPP-1; Cell growth-inhibiting gene 1 protein; Lysosomal pepstatin-insensitive protease; LPIC; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase I; TPP-I
Clone
K1H013_12G7
Conjugation
Unconjugated
Applications
Top_IHC&Top_WB
Validation
Top_IHC&Top_WB
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%, Pig - 92%, Cynomolgus monkey - 98%
Purity
≥85%
Cores
TPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTL
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
90%
Recombinant Antibody
Yes
IHC Dilution
1:3000~1:4000
WB Dilution
1:1000
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
CLN2
Target Alternative Name
TPP1
Panel Description
Neurodegenerative Diseases Marker
Host or Source
Mouse
Protein Name
Tripeptidyl peptidase 1
WB Description
Succeed
IHC description
Succeed
IP description
Fail (Hep G2)
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2a

UniProtKB · O14773

Tripeptidyl-peptidase 1

TPP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14773
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TPP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TPP-1
EC number
3.4.14.9
Processing
Precursor
Secondary accessions
Q53HT1, Q5JAK6, Q6UX56, Q71JP6, Q96C37
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Autocatalytic cleavageDisulfide bondGlycoproteinZymogen

Ligand

CalciumMetal-binding

Disease

Disease variantEpilepsyNeurodegenerationNeuronal ceroid lipofuscinosisSpinocerebellar ataxia

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Lysosome

Domain

Signal

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