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HMGCR Antibody

CAT: 0667-KC-1203-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-1203-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase
Gene Name
HMGCR
Gene ID
3156
UniProt
P04035
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human HMGCR
Target
PP-4354
Partner Proteins
3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase
Clone
K70036_4B11
Conjugation
Unconjugated
Applications
IHC
Validation
IHC
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%, Pig - 83%, Cynomolgus monkey - 96%
Purity
≥85%
Cores
KNPITSPVVTQKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAK
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
76%
Recombinant Antibody
Not recombinant
IHC Dilution
1:200
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
/
Target Alternative Name
HMGCR
Panel Description
Autoimmune Disease, Ferroptosis
Host or Source
Mouse
Protein Name
3-Hydroxy-3-methylglutaryl-CoA reductase
IHC description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2a

UniProtKB · P04035

3-hydroxy-3-methylglutaryl-coenzyme A reductase

HMDH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04035
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HMGCR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HMG-CoA reductase
EC number
1.1.1.34
Processing
—
Secondary accessions
B7Z3Y9, Q8N190
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cholesterol biosynthesisCholesterol metabolismLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol biosynthesisSterol metabolism

Disease

Disease variantLimb-girdle muscular dystrophy

Cellular component

Endoplasmic reticulumMembranePeroxisome

PTM

GlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Ligand

NADP

Molecular function

Oxidoreductase

Domain

TransmembraneTransmembrane helix

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