MDA5 Antibody

• Product Name Alternative:

  Interferon-induced helicase C domain-containing protein 1, Clinically amyopathic dermatomyositis autoantigen 140 kDa, CADM-140 autoantigen, Helicase with 2 CARD domains, Helicard, Interferon-induced with helicase C domain protein 1, Melanoma differentiation-associated protein 5, MDA-5, Murabutide down-regulated protein, RIG-I-like receptor 2, RLR-2, RNA helicase-DEAD box protein 116

• Gene Name:

  IFIH1

• Gene ID:

  64135

• UniProt:

  Q9BYX4

• Antigen Species:

  Human

• Reactivity:

  Human

• Cross Reactivity:

  Not tested

• Immunogen:

  Recombinant human IFIH1

• Target:

  PP-5396

• Partner Proteins:

  Interferon-induced helicase C domain-containing protein 1; Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domain protein 1; Melanoma differentiation-associated protein 5; MDA-5; Murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116

• Clone:

  K52010_3G10

• Conjugation:

  Unconjugated

• Applications:

  Top_IHC

• Validation:

  Top_IHC

• Homology:

  Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 27%, Pig - 85%, Cynomolgus monkey - 99%

• Purity:

  ≥85%

• Cores:

  QIQEPCKKFAIADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQAR

• Storage Temperature:

  Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower

• Identity Mouse:

  83%

• Recombinant Antibody:

  Not recombinant

• IHC Dilution:

  1:200

• Formulation:

  Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide

• Antibody Type:

  Monoclonal

• Gene Name Synonym:

  MDA5; RH116

• Target Alternative Name:

  MDA5

• Panel Description:

  Autoimmune Disease

• Host or Source:

  Mouse

• Protein Name:

  Interferon induced with helicase C domain 1

• IHC description:

  Succeed

• IP description:

  Fail (THP-1 (LPS) )

• Shipping Temperature:

  Shipped at ambient temperature or with ice packs.

• Isotype:

  IgG2a