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Pyruvate Dehydrogenase E2 Antibody

CAT: 0667-KC-956-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-956-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, M2 antigen complex 70 kDa subunit, Pyruvate dehydrogenase complex component E2, PDC-E2, PDCE2
Gene Name
DLAT
Gene ID
1737
UniProt
P10515
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human DLAT
Target
PP-4746
Partner Proteins
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; mitochondrial; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; PBC; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; M2 antigen complex 70 kDa subunit; Pyruvate dehydrogenase complex component E2; PDC-E2; PDCE2
Clone
K29029_13C6
Conjugation
Unconjugated
Applications
Top_IHC&Top_IP/ChIP&Top_WB&ICC/IF
Validation
Top_IHC&Top_IP/ChIP&Top_WB&ICC/IF
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%, Pig - 90%, Cynomolgus monkey - 98%
Purity
≥85%
Cores
HQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGP
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
85%
Recombinant Antibody
Not recombinant
IHC Dilution
1:100
WB Dilution
1:1000
IP Dilution
1:100
IF Dilution
1:250
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
DLTA
Target Alternative Name
Pyruvate Dehydrogenase E2
Panel Description
Autoimmune Disease, Neurodegenerative Diseases Marker
Host or Source
Mouse
Protein Name
Dihydrolipoamide S-acetyltransferase
WB Description
Succeed
IHC description
Succeed
IF/ICC description
Succeed
IP description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · P10515

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

ODP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P10515
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DLAT
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.1.12
Processing
Precursor
Secondary accessions
Q16783, Q53EP3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

AcyltransferaseTransferase

Biological process

Carbohydrate metabolismGlucose metabolismTricarboxylic acid cycle

Domain

LipoylRepeatTransit peptide

Cellular component

Mitochondrion

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