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BRAF V600E Antibody

CAT: 0667-KC-2309-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-2309-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1
Gene Name
BRAF
Gene ID
673
UniProt
P15056
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Synthetic peptide within aa593-606 of human BRAF.
Target
SP02554EA
Partner Proteins
Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1
Clone
K16226_4B10
Conjugation
Unconjugated
Applications
Top_IP/ChIP
Validation
Top_IP/ChIP
Purity
≥85%
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Recombinant Antibody
Not recombinant
IP Dilution
1:100
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
BRAF1; RAFB1
Target Alternative Name
BRAF V600E
Panel Description
IHC Pathology
Host or Source
Mouse
Protein Name
B-Raf proto-oncogene, serine/threonine kinase
WB Description
Fail (A-375, U-251MG)
IP description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2b

UniProtKB · P15056

Serine/threonine-protein kinase B-raf

BRAF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15056
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRAF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A4D1T4, B6HY61, B6HY62, B6HY63, B6HY64, B6HY65, B6HY66, Q13878, Q3MIN6, Q9UDP8, Q9Y6T3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

Allosteric enzymeKinaseSerine/threonine-protein kinaseTransferase

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

CardiomyopathyDeafnessDisease variantEctodermal dysplasiaIntellectual disabilityProto-oncogene

Cellular component

Cell membraneCytoplasmMembraneNucleus

Coding sequence diversity

Chromosomal rearrangement

Domain

Zinc-finger

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