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PD-L1 Antibody

CAT: 0667-KC-434-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-434-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD antigen CD274
Gene Name
CD274
Gene ID
29126
UniProt
Q9NZQ7
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Extracellular region of human PD-L1
Target Antigen
CD274
Target
P00657PCGND
Partner Proteins
Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; hPD-L1; B7 homolog 1; B7-H1; CD antigen CD274
Clone
K06145_2C7
Conjugation
Unconjugated
Applications
Top_IHC&ELISA&FC
Validation
Top_IHC&ELISA&FC
Detection Method
Succeed
Dilution
1:100
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 31%, Pig - 80%, Cynomolgus monkey - 96%
Purity
≥85%
Cores
VTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELP
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
73%
Recombinant Antibody
Not recombinant
IHC Dilution
1:250
Sandwich ELISA Dilution
1:200
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
B7H1; PDCD1L1; PDCD1LG1; PDL1
Target Alternative Name
PD-L1
Panel Description
CD Antigen
Host or Source
Mouse
Protein Name
CD274 molecule
IHC description
Succeed
FC description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2a

UniProtKB · Q9NZQ7

Programmed cell death 1 ligand 1

PD1L1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZQ7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD274
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1
EC number
—
Processing
Precursor
Secondary accessions
B2RBA2, B4DU27, Q14CJ2, Q2V8D5, Q66RK1, Q6WEX4, Q9NUZ5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndosomeMembraneNucleusSecreted

Disease

Diabetes mellitus

PTM

Disulfide bondGlycoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Receptor

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