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1β-Hydroxydeoxycholic acid

CAT: 0804-HY-113482-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113482-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1β-Hydroxydeoxycholic acid (1β-OH-DCA), a secondary bile acid, is a CYP3A biomarker. Deoxycholic acid is specifically metabolized into 1β-Hydroxydeoxycholic acid by CYP3A4 and CYP3A7 using recombinant human CYP450 enzymes[1].
CAS Number
80434-32-8
Product Name Alternative
1β-OH-DCA
UNSPSC
12352211
Target
Cytochrome P450; Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/1β-hydroxydeoxycholic-acid.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@@H](C[C@H]2O)O)([H])[C@@]4([H])[C@]([C@H](C3)O)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C
Molecular Formula
C24H40O5
Molecular Weight
408.57
References & Citations
[1]Gaëlle Magliocco, et al. The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker? J Pers Med. 2021 Feb 20;11 (2) :150.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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