DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8

DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8

• CAS Number: 108641-82-3
• UNSPSC Description: DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8 is the deuterium labeled DL-Homocystine. DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia[1][2].
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Purity: 98.0
• Solubility: H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: C(C(C(O)=O)N)(C(SSC(C(C(C(O)=O)N)([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H]
• Molecular Weight: 276.40
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Brown AS, et al. Homocysteine and schizophrenia: from prenatal to adult life. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Sep;29(7):1175-80.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported