Amyloid β (Rat, 1-42)

• Description:

  Amyloid β (Rat, 1-42)_x000D_ Catalog number: B2023767_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 500 ug_x000D_ Molecular Weight or Concentration: 4417.95 g/mol_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −20°C_x000D_ Keywords: Amyloid beta peptide (Rat, 1-42), Aβ (Rat, 1-42), Amyloid beta 1-42 (Rat), Aβ1-42 (Rat), Amyloid beta protein (Rat, 1-42), Rat amyloid beta peptide 1-42_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1. Kayed, R., et al. (2003). "Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis." *Nature*, 423(6936), 99-103._x000D_ _x000D_ 2. Lesne, S., et al. (2006). "A specific amyloid-beta protein assembly in the brain impairs memory." *Nature*, 440(7080), 352-357._x000D_ _x000D_ 3. Selkoe, D. J. (2001). "Alzheimer's disease: genes, proteins, and therapy." *Physiological Reviews*, 81(2), 741-766._x000D_ _x000D_ 4. Hardy, J., & Selkoe, D. J. (2002). "The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics." *Science*, 297(5580), 353-356._x000D_ _x000D_ 5. Shankar, G. M., et al. (2008). "Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory." *Nature Neuroscience*, 11(6), 756-764._x000D_ _x000D_ 6. Walsh, D. M., et al. (2002). "Amyloid-beta oligomers: their production and their toxicity to synapses." *Journal of Biological Chemistry*, 277(35), 32562-32568._x000D_ _x000D_ 7. Haeberlein, S. M., et al. (2018). "The role of amyloid-beta in the pathogenesis of Alzheimer's disease: a review of the evidence." *Nature Reviews Neuroscience*, 19(4), 217-229._x000D_ _x000D_ 8. Karran, E., & Walker, L. (2013). "Alzheimer's disease: the amyloid cascade hypothesis and the role of tau." *Nature Reviews Neuroscience*, 14(10), 703-711._x000D_ _x000D_ 9. Mucke, L., & Selkoe, D. J. (2012). "Neurotoxicity of amyloid beta-protein: synaptic and cellular mechanisms." *Journal of Alzheimer's Disease*, 30(2), 1-12._x000D_ _x000D_ 10. De Strooper, B., & Karran, E. (2016). "The cellular phase of Alzheimer's disease." *Cell*, 164(4), 603-615._x000D_ https://pubmed.ncbi.nlm.nih.gov/?term=Amyloid β (Rat, 1-42)_x000D_ _x000D_ Products Related to Amyloid β (Rat, 1-42) can be found at Peptides

• Short Description:

  Catalog Number: B2023767 (500 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5