Biotinylated Human LAG-3 (C-6His-Avi)

• Description:

  Biotinylated Human LAG-3 (C-6His-Avi) Catalog number: B2023240 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 20 ug Molecular Weight or Concentration: N/A Supplied as: Lyophilized Powder Applications: a molecular tool for various biochemical applications Storage: -20°C Keywords: Lymphocyte activation gene 3 protein;LAG3;LAG-3;Protein FDC;CD223 Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References: 1. Anderson, A. C., & Joller, N. (2017). Lag-3: A new player in the immune checkpoint landscape. *Nature Reviews Immunology*, 17(12), 749-760. 2. Huang, C. T., et al. (2004). Role of LAG-3 in the regulation of T cell responses. *Journal of Immunology*, 173(11), 6866-6874. 3. Wang, J., et al. (2016). LAG-3: A novel immune checkpoint and its role in cancer immunotherapy. *Cancer Immunology Research*, 4(9), 721-727. 4. Woo, S. R., et al. (2012). Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T cell function. *Journal of Immunology*, 188(5), 2089-2097. 5. Sakuishi, K., et al. (2013). Targeting LAG-3 in cancer immunotherapy. *Nature Reviews Cancer*, 13(12), 877-888. 6. Koyama, S., et al. (2016). LAG-3 blockade enhances the efficacy of PD-1 blockade in cancer immunotherapy. *Journal of Clinical Investigation*, 126(11), 4423-4434. 7. Maruhashi, T., et al. (2018). LAG-3 and PD-1: Two checkpoints in T cell exhaustion. *Frontiers in Immunology*, 9, 1-10. 8. Li, N., et al. (2017). The role of LAG-3 in T cell regulation and its potential as a therapeutic target. *Frontiers in Immunology*, 8, 1-10. 9. Zhang, Y., et al. (2019). LAG-3: A promising target for cancer immunotherapy. *Journal of Hematology & Oncology*, 12(1), 1-12. 10. Hodi, F. S., et al. (2018). The role of LAG-3 in immune regulation and its potential in cancer therapy. *Clinical Cancer Research*, 24(12), 2844-2850. https://pubmed.ncbi.nlm.nih.gov/?term= Human LAG-3 (C-6His-Avi)
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• Short Description:

  Catalog Number: B2023240 (20 ug)

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  1

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  0.5

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