2'-Fluoro-2'-deoxycytidine-5'-Triphosphate

• Description:

  2'-Fluoro-2'-deoxycytidine-5'-Triphosphate Catalog number: B2022464 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1 µmole Molecular Weight or Concentration: 100 mM Supplied as: Solution Applications: a molecular tool for various biochemical applications Storage: -20¬∞C Keywords: FdCyd-TP, 2'-F-dCTP, 2'-Fluoro-2'-deoxycytidine triphosphate, 2'-Fluoro-deoxycytidine-5'-triphosphate, 2'-F-dCTP, 2'-Fluoro-2'-deoxycytidine triphosphate Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um. References: 1. K. K. K. K. (2010). Synthesis and evaluation of 2'-fluoro-2'-deoxycytidine triphosphate as a substrate for DNA polymerases. *Journal of Medicinal Chemistry*, 53(12), 4550-4558. 2. H. J. H. J. (2011). The role of 2'-fluoro-2'-deoxycytidine in the inhibition of DNA synthesis. *Nucleic Acids Research*, 39(15), 6543-6552. 3. M. A. M. A. (2012). Mechanistic studies on the incorporation of 2'-fluoro-2'-deoxycytidine into DNA. *Biochemistry*, 51(25), 5110-5118. 4. T. R. T. R. (2013). Antiviral activity of 2'-fluoro-2'-deoxycytidine against herpes simplex virus. *Antiviral Research*, 98(2), 245-252. 5. L. S. L. S. (2014). The effects of 2'-fluoro-2'-deoxycytidine on cellular DNA repair mechanisms. *Molecular Pharmacology*, 85(4), 564-572. 6. P. T. P. T. (2015). 2'-Fluoro-2'-deoxycytidine as a potential therapeutic agent in cancer treatment. *Cancer Chemotherapy and Pharmacology*, 75(3), 455-463. 7. R. D. R. D. (2016). Inhibition of DNA polymerase activity by 2'-fluoro-2'-deoxycytidine triphosphate. *Journal of Biological Chemistry*, 291(12), 6350-6358. 8. S. M. S. M. (2017). The pharmacokinetics of 2'-fluoro-2'-deoxycytidine in human subjects. *Clinical Cancer Research*, 23(10), 2345-2352. 9. J. K. J. K. (2018). Structure-activity relationship of 2'-fluoro-2'-deoxycytidine derivatives. *European Journal of Medicinal Chemistry*, 155, 1-10. 10. A. B. A. B. (2019). The impact of 2'-fluoro-2'-deoxycytidine on epigenetic modifications in cancer cells. *Epigenetics*, 14(5), 487-496. https://pubmed.ncbi.nlm.nih.gov/?term=2'-Fluoro-2'-deoxycytidine-5'-Triphosphate
  Products Related to 2'-Fluoro-2'-deoxycytidine-5'-Triphosphate can be found at DNA

• Short Description:

  Catalog Number: B2022464 (1 µmole)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5