Echistatin, α1 isoform

• Description :

  Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM) . Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM) . Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  5417.1

• Molecular Formula :

  C217H341N71O74S9

• Notes :

  Research use only, not for human use.

• Receptor :

  ——

• CAS Number :

  154303-05-6