Α-Conotoxin MII

• Description:

  Highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in Xenopus oocytes) . Also potently blocks β3-containing neuronal nicotinic receptors. Displays > 200-fold selectivity for α3β2 over α2β2, α4β2 and α3β4.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  1710.99

• Molecular Formula:

  C67H103N23O22S4

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  175735-93-0