GR 231118

• Description:

  Potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively) . Also a potent and selective NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively) . Suppresses food intake in rats in vivo. Also has affinity for neuropeptide FF (NPFF) receptors in vitro (Ki = 43-73 nM) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  2352.77

• Molecular Formula:

  C110H170N34O24

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  158859-98-4