JKC 363

• Description:

  Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, attenuates food intake and reduces formalin-induced pain in vivo.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  1506.72

• Molecular Formula:

  C69H91N19O16S2

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  436083-30-6