MSG 606

• Description:

  Potent human MC1 receptor antagonist (IC50 = 17 nM) . Also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively) . Exhibits binding affinity for A375 melanoma cells in vitro. Reverses morphine-induced hyperalgesia in female mice, with no effect in male mice. γMSH analog.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  1347.51

• Molecular Formula:

  C62H82N20O13S

• Notes:

  Research use only, not for human use.

• Receptor:

  ——

• CAS Number:

  1416983-77-1