MM 54

• Description :

  Potent apelin receptor antagonist (Ki = 82 nM; IC50 = 93 nM) . Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  1737.15

• Molecular Formula :

  C70H121N29O15S4

• Notes :

  Research use only, not for human use.

• Receptor :

  ——

• CAS Number :

  1313027-43-8