ShK-Dap22

• Description :

  Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents) . Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4) . Suppresses T cell activation in vitro (IC50 < 500 pM) .

• CAS Number :

  220384-25-8

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  4012.7

• Molecular Formula :

  C166H268N54O48S7

• Notes :

  Research use only, not for human use.

• Receptor :

  ——