Urocortin, human

• Description:

  Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively. Urocortin human can be used as a test compound for studying the impact of corticotropin-releasing factor (CRF) receptor agonist and antagonist on sleep-wake patterns in conscious rats by using radiotelemetry system.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  4696.24

• Molecular Formula:

  C204H337N63O64

• Notes:

  Research use only, not for human use.

• Receptor:

  Ki: 0.4 nM (hCRF1, cell assay), 0.3 nM (rCRF2α, cell assay), and 0.5 nM (mCRF2β, cell assay)

• CAS Number:

  176591-49-4