NecroX-7 B

CAT: 1410-M37704-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M37704-01Size:1 g
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Description
NecroX-7 (LC-280126) is a potent free radical scavenger and HMGB1 (high-mobility group box 1) inhibitor. It serves as an antidote to acetaminophen toxicity and exerts a protective effect by preventing HMGB1 release in ischemia/reperfusion injury. Additionally, NecroX-7 inhibits HMGB1-induced release of TNF and IL-6 and the expression of TLR-4 and receptor for advanced glycation end products. This compound may be used for graft-versus-host disease (GVHD) research .
CAS Number
1120332-55-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
439.57
Molecular Formula
C24H29N3O3S
Notes
Research use only, not for human use.
Receptor
NADPH-oxidase

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