AZD-4877

• Description:

  AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  503.66

• Molecular Formula:

  C28H33N5O2S

• Notes:

  Research use only, not for human use.

• Receptor:

  Apoptosis | Kinesin

• CAS Number:

  758722-49-5