TNIK-IN-3

• Description:

  TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK) . It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 μM. Additionally, TNIK-IN-3 demonstrates inhibitory activity against Flt4 (IC50 = 0.030 μM), Flt1 (IC50 = 0.191 μM), and DRAK1 (IC50 = 0.411 μM) . This compound holds potential for carrying out research on colorectal cancer (CRC) .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  387.41

• Molecular Formula:

  C23H18FN3O2

• Notes:

  Research use only, not for human use.

• Receptor:

  Wnt/beta-catenin

• CAS Number:

  2754265-25-1