Nrf2-IN-3

• Description:

  Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  442.53

• Molecular Formula:

  C22H26N4O4S

• Notes:

  Research use only, not for human use.

• Receptor:

  Nrf2

• CAS Number:

  6325-13-9