Nrf2-IN-3

• Description :

  Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.

• CAS Number :

  6325-13-9

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  442.53

• Molecular Formula :

  C22H26N4O4S

• Notes :

  Research use only, not for human use.

• Receptor :

  Nrf2