Ponsegromab

• Description:

  Ponsegromab (PF 06946860) is a selective and effective humanized anti-GDF15 antibody inhibitor with anti-cachexic activity. It binds to GDF15, preventing its interaction with GFRAL and disrupting GDF15/GFRAL mediated signaling. Ponsegromab has potential anticancer activity and can be used to treat cancer patients with cancer anorexia cachexia syndrome.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Molecular Formula:

  ——

• Notes:

  Research use only, not for human use.

• Receptor:

  TGF-beta/Smad

• CAS Number:

  2368950-15-4