SLC26A3-IN-2

• Description:

  SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, with an IC50 of 360 nM. This protein, a member of the solute carrier (SLC) family SLC26, has broad anion specificity including chloride, bicarbonate, sulfate, and oxalate. SLC26A3, also known as DRA, is typically down-regulated in adenoma and plays a crucial role in intestinal absorption of chloride and oxalate. Mutations causing loss of SLC26A3 function are associated with chloride-losing diarrhea .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  368.84

• Molecular Formula:

  C19H13ClN2O2S

• Notes:

  Research use only, not for human use.

• Receptor:

  Others

• CAS Number:

  950348-60-4