Products for Research Use Only
RegisterLogin

EB1

CAT: 1410-M36547-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M36547-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the growth of cancer cells, promotes apoptosis, and inhibits the phosphorylation of eIF4E.
CAS Number
42951-68-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
286.33
Molecular Formula
C18H14N4
Notes
Research use only, not for human use.
Receptor
MNK

Chemical Information

4,6-diphenyl-1H-pyrazolo[3,4-b]pyridin-3-amine
CAS Number42951-68-8
PubChem CID2048804
IUPAC Name4,6-diphenyl-2H-pyrazolo[3,4-b]pyridin-3-amine
Molecular FormulaC18H14N4
Molecular Weight286.3
XLogP3.8
Topological Polar Surface Area67.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count22
Formal Charge0
Complexity362
SMILES
C1=CC=C(C=C1)C2=CC(=NC3=NNC(=C23)N)C4=CC=CC=C4
InChI
InChI=1S/C18H14N4/c19-17-16-14(12-7-3-1-4-8-12)11-15(20-18(16)22-21-17)13-9-5-2-6-10-13/h1-11H,(H3,19,20,21,22)
InChIKey
NGNHXYCLUMQSKR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4,6-diphenyl-1H-pyrazolo[3,4-b]pyridin-3-amine
CAS: 42951-68-8
CID: 2048804
Formula: C18H14N4
MW: 286.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight286.3
XLogP33.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass286.121846464
Monoisotopic Mass286.121846464
Topological Polar Surface Area67.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity362
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
303-150Riboclear (RNA Cleanup)
TBS10485-100Tribio InVivoMAb Anti-Mouse TIGIT & PD-L1 Bispecific Antibody
TBS10191-1mgTetrahydrocannabinol (THC) Monoclonal Antibody
TBI3024-25MGAc-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor
122-101ExgeneTM Forensic SV mini
TBS10483-100Tribio InVivoMAb Anti-Mouse PD-L1 & CD28 Bispecific Antibody
TBS10183-1mgMonoclonal Anti-Thyroid Stimulating Hormone (TSH) Antibody
TBS10340-0.5MGInVivo Mouse IgG1 Isotype Control Antibody
121-220Exfection Plasmid EF (Exdotoxin Free, Midi)
TBS10482-100Tribio InVivoMAb Anti-Mouse PD-L1 & OX40 Bispecific Antibody

Popular Products