Pitavastatin

• Description:

  Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC50 of 5.8 nM. It also induces hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptors and exhibits therapeutic activities such as anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective, and reno-protective effects.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  421.46

• Molecular Formula:

  C25H24FNO4

• Notes:

  Research use only, not for human use.

• Receptor:

  Autophagy | HMG-CoA Reductase | Apoptosis | Mitophagy

• CAS Number:

  147511-69-1