BI-0474

• Description :

  BI-0474 is a potent KRASG12C inhibitor that inhibits GDP-KRAS::SOS1 protein-protein interactions with an IC50 value of 7.0 nM.BI-0474 exhibits significant antiproliferative activity against NCI-H358 cells harboring the G12C mutation, and shows significant anti-tumor activity in a non-small cell lung cancer xenograft model. activity.BI-0474 can be used for cancer research.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  587.74

• Molecular Formula :

  C30H37N9O2S

• Notes :

  Research use only, not for human use.

• Receptor :

  Kras

• CAS Number :

  2750570-55-7