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BI-0474

CAT: 1410-M36283-01Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M36283-01Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI-0474 is a potent KRASG12C inhibitor that inhibits GDP-KRAS::SOS1 protein-protein interactions with an IC50 value of 7.0 nM.BI-0474 exhibits significant antiproliferative activity against NCI-H358 cells harboring the G12C mutation, and shows significant anti-tumor activity in a non-small cell lung cancer xenograft model. activity.BI-0474 can be used for cancer research.
CAS Number
2750570-55-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
587.74
Molecular Formula
C30H37N9O2S
Notes
Research use only, not for human use.
Receptor
Kras

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BUP00850-01BI-0474
A24574-10BI-0474 10mg
A24574-100BI-0474 100mg
A24574-50BI-0474 50mg
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