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TH1760

CAT: 1410-M36034-01Size: 1 EachDry Ice: NoHazardous: No
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Description
TH1760 (MKB) is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM) . TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia effect of thiopurine.
CAS Number
2567914-01-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
426.45
Molecular Formula
C20H18N4O5S
Notes
Research use only, not for human use.
Receptor
NUDIX hydrolase

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