HOIPIN-8 sodium

CAT: 1410-M35672-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M35672-01Size:1 g
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Description
HOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. As a derivative of HOIPIN-1, it exhibits 255-fold greater inhibition of both petit-LUBAC and TNF-α-mediated NF-κB activation compared to HOIPIN-1. HOIPIN-8 is a promising tool to explore cellular functions of LUBAC.
CAS Number
2519537-70-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
456.38
Molecular Formula
C23H15F2N4NaO3
Notes
Research use only, not for human use.
Receptor
IκB/IKK

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