Products for Research Use Only
RegisterLogin

EAI001

CAT: 1410-M35525-01Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M35525-01Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.EAI001 can be used in cancer research.
CAS Number
892772-75-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
349.41
Molecular Formula
C19H15N3O2S
Notes
Research use only, not for human use.
Receptor
EGFR

Chemical Information

2-(1-oxoisoindolin-2-yl)-2-phenyl-N-(thiazol-2-yl)acetamide
CAS Number892772-75-7
PubChem CID45370166
IUPAC Name2-(3-oxo-1H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide
Molecular FormulaC19H15N3O2S
Molecular Weight349.4
XLogP2.9
Topological Polar Surface Area90.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity509
SMILES
C1C2=CC=CC=C2C(=O)N1C(C3=CC=CC=C3)C(=O)NC4=NC=CS4
InChI
InChI=1S/C19H15N3O2S/c23-17(21-19-20-10-11-25-19)16(13-6-2-1-3-7-13)22-12-14-8-4-5-9-15(14)18(22)24/h1-11,16H,12H2,(H,20,21,23)
InChIKey
PWRVRDCBFYLYFU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(1-oxoisoindolin-2-yl)-2-phenyl-N-(thiazol-2-yl)acetamide
CAS: 892772-75-7
CID: 45370166
Formula: C19H15N3O2S
MW: 349.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight349.4
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass349.08849790
Monoisotopic Mass349.08849790
Topological Polar Surface Area90.5 Ų
Heavy Atom Count25
Formal Charge0
Complexity509
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M17407-01EAI045

Alternative Products

CatalogName
HY-100214-01EAI001
HY-100214REAI001 (Standard)

Popular Products