(1S,2R) -Alicapistat

• Description:

  (1S,2R) -Alicapistat ((1S,2R) -ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, showing promise for Alzheimer's disease (AD) therapy . It effectively addresses the metabolic liability associated with carbonyl reduction and demonstrates potent inhibition of calpain 1 with an IC50 value of 395 nM .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  433.5

• Molecular Formula:

  C25H27N3O4

• Notes:

  Research use only, not for human use.

• Receptor:

  Cysteine Protease

• CAS Number:

  2221010-57-5