AY 77

• Description:

  AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM) . AY 77 can promote migration of human breast cancer cells in vitro.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  404.5

• Molecular Formula:

  C21H32N4O4

• Notes:

  Research use only, not for human use.

• Receptor:

  Protease-activated Receptor | Calcium Channel | ERK

• CAS Number:

  1835734-92-3