CBR-470-1

• Description:

  CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  365.9

• Molecular Formula:

  C14H20ClNO4S2

• Notes:

  Research use only, not for human use.

• Receptor:

  Nrf2

• CAS Number:

  2416095-06-0