(S) -Coriolic acid

CAT: 1410-M34990-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M34990-01Size:1 g
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Description
(S) -Coriolic acid (13 (S) -HODE) is an important intracellular signaling agent generated by the reaction of linoleic acid with plant and mammalian lipoxygenases. It is involved in cell proliferation and differentiation in various biological systems and inhibits the adhesion of tumor cells to the vascular endothelium, while down-regulating IRGpIIb/IIIa receptor expression at around 1 μM. Additionally, (S) -Coriolic acid is a metabolite of 15-lipoxygenase (15-LOX) and often acts as an endogenous ligand to activate PPARγ. It induces mitochondrial dysfunction and airway epithelial damage.
CAS Number
29623-28-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
296.44
Molecular Formula
C18H32O3
Notes
Research use only, not for human use.
Receptor
Lipoxygenase | Mitochondrial Metabolism | PPAR

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