Necrostatin-5

• Description:

  Necrostatin-5 (Nec-5) is a selective RIP1 kinase inhibitor and cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α, with an EC50 of 240 nM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  383.49

• Molecular Formula:

  C19H17N3O2S2

• Notes:

  Research use only, not for human use.

• Receptor:

  RIP kinase | Necroptosis

• CAS Number:

  337349-54-9