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Enpatoran hydrochloride

CAT: 1410-M34931-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:1410-M34931-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enpatoran (M5049) hydrochloride is a potent, orally active dual inhibitor of TLR7/8 with IC50 values of 11.1 nM and 24.1 nM in HEK293 cells, respectively. This compound specifically inhibits TLR7 and TLR8 without affecting TLR3, TLR4, or TLR9, and blocks both synthetic molecule ligands and natural endogenous RNA ligands. Enpatoran hydrochloride also exhibits excellent pharmacokinetic properties in vivo, making it a valuable tool for studying and modulating innate and adaptive autoimmunity.
CAS Number
2101945-93-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
356.78
Molecular Formula
C16H16ClF3N4
Notes
Research use only, not for human use.
Receptor
Others

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