Rolapitant hydrochloride B

• Description:

  Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  536.94

• Molecular Formula:

  C25H27ClF6N2O2

• Notes:

  Research use only, not for human use.

• Receptor:

  Neurokinin receptor

• CAS Number:

  858102-79-1