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BPHA

CAT: 1410-M34878-01Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M34878-01Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000 and 795 nM, respectively) .BPHA has anti-angiogenic and BPHA has anti-angiogenic and anti-tumor activities.
CAS Number
193807-60-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
396.46
Molecular Formula
C21H20N2O4S
Notes
Research use only, not for human use.
Receptor
MMP

Chemical Information

(2R)-((4-biphenylylsulfonyl)amino)-N-hydroxy-3-phenylpropionamide

structure in first source

CAS Number193807-60-2
PubChem CID9822095
IUPAC Name(2R)-N-hydroxy-3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanamide
Molecular FormulaC21H20N2O4S
Molecular Weight396.5
XLogP3.4
Topological Polar Surface Area104
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Heavy Atom Count28
Formal Charge0
Complexity584
SMILES
C1=CC=C(C=C1)C[C@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3
InChI
InChI=1S/C21H20N2O4S/c24-21(22-25)20(15-16-7-3-1-4-8-16)23-28(26,27)19-13-11-18(12-14-19)17-9-5-2-6-10-17/h1-14,20,23,25H,15H2,(H,22,24)/t20-/m1/s1
InChIKey
UPCAIRKRFXQRRM-HXUWFJFHSA-N
Chemical Structure
2D Structure
2D structure of (2R)-((4-biphenylylsulfonyl)amino)-N-hydroxy-3-phenylpropionamide
CAS: 193807-60-2
CID: 9822095
Formula: C21H20N2O4S
MW: 396.5
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight396.5
XLogP33.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass396.11437830
Monoisotopic Mass396.11437830
Topological Polar Surface Area104 Ų
Heavy Atom Count28
Formal Charge0
Complexity584
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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