Dehydro Nifedipine

• Description:

  Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  344.32

• Molecular Formula:

  C17H16N2O6

• Notes:

  Research use only, not for human use.

• Receptor:

  Drug Metabolite

• CAS Number:

  67035-22-7