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Chlorin E6

CAT: 1410-M34843-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:1410-M34843-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiation) resulted in complete tumor disappearance after varying degrees of irradiation. Agents including Chlorin E6 were tested in a Phase I clinical study in patients with early superficial squamous cell carcinoma of bronchial origin with favorable results (40 mg/m2, IV, 100 J/cm2 laser irradiation) . In a Phase II clinical trial in patients with early stage lung cancer, the same mode of administration resulted in a complete response in 82.9% of patients. Chlorin E6 has been investigated as a nanotechnology drug delivery tool.
CAS Number
19660-77-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
596.67
Molecular Formula
C34H36N4O6
Notes
Research use only, not for human use.
Receptor
Parasite

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