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Furosemide sodium

CAT: 1410-M34751-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:1410-M34751-01Size:25 mg
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Description
Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
CAS Number
41733-55-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
352.73
Molecular Formula
C12H10ClN2NaO5S
Notes
Research use only, not for human use.
Receptor
GABA Receptor | Na-K-Cl cotransporter

Chemical Information

Sodium furosemide
CAS Number41733-55-5
PubChem CID23673593
IUPAC Namesodium 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate
Molecular FormulaC12H10ClN2NaO5S
Molecular Weight352.73
Topological Polar Surface Area134
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count22
Formal Charge0
Complexity486
SMILES
C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)[O-])S(=O)(=O)N)Cl.[Na+]
InChI
InChI=1S/C12H11ClN2O5S.Na/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19;/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);/q;+1/p-1
InChIKey
DLFCAVBMDSKMEY-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of Sodium furosemide
CAS: 41733-55-5
CID: 23673593
Formula: C12H10ClN2NaO5S
MW: 352.73
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight352.73
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass351.9896646
Monoisotopic Mass351.9896646
Topological Polar Surface Area134 Ų
Heavy Atom Count22
Formal Charge0
Complexity486
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes